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Chagas Disease: Current Status and Future Therapeutic Directions

San Diego, CA

12/5/2017

8:00am - 5:15pm

Neglected tropical diseases (NTDs) are a diverse group of communicable diseases affecting approximately 20% of the world’s population. They are present in 149 countries and negatively impact both the socio-economic development and health of individuals in developing countries. The London Declaration on Neglected Tropical Diseases has committed to containing or eliminating 10 of these diseases by 2020 including Chagas Disease.
This disease, first described by Carlos Chagas in 1909, is an infection caused by the parasite Trypanosoma cruzi (T.cruzi). The disease is endemic in Latin American countries, with an increasing number of cases detected in the United States, Australia, and Japan. Currently,11 million people are infected with the disease, and it is recognized as an emerging infection in many countries including the US, Japan, Spain and Australia. Although it has become a leading cause of heart failure in several countries, the only drugs that are approved are benznidazole and nifurtimox. Both of these drugs have severe side effects such as neurological effects, allergic dermatitis, and GI intolerance in addition to a lack of efficacy on late-stage disease. As a result, there is a need for new approaches and drugs to treat the disease.
This symposium will bring together the latest research that is occurring in Chagas disease today with the goal of understanding the gaps and proposing potential solutions. There will be several seminars followed by a round table discussion led by Dr. Jim McKerrow, Dean, Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego.

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Contact: Michelle Maiello
Contact Phone: 8582421533
Contact Email: mmaiello@its.jnj.com

Event Address:

Janssen Research & Development
3210 Merryfield Row
San Diego, CA