The Growing Antimicrobial Resistance Challenge

Antimicrobial resistance (AMR) is a major threat to Public Health. According to the World Health Organization, there are an estimated 700,000 deaths worldwide each year as a result of bacterial infections. The US Center for Disease Control and Prevention (CDC) estimates that in the US alone, 23,000 people die each year from drug-resistant bacterial infections.

Global Movement to Combat Antimicrobial Resistance

CARB-X is one of the world’s largest public-private partnerships dedicated to accelerating antibacterial innovation. It has the world’s largest antibacterial pipeline focused specifically on combating drug resistant bacteria, especially Gram-negative bacteria, and it supports research projects in companies around the world. CARB-X is investing more than $500 million between 2016-2021 in the development of antibiotics and other life-saving therapeutics of all types, diagnostics, vaccines and other preventatives and devices. California Life Sciences Institute (CLSI) is a vital part of CARB-X’s network of accelerators and provides business and technical support to funded projects throughout the world.

To learn more about CARB-X and funding opportunities, please consult the CARB-X website at https://carb-x.org/

We would be happy to answer your questions about CARB-X and share more ways you can get involved.
Julie Harness
Senior Director
[email protected]

FAST International: Canada Canadian Technology Accelerator Program

The Canadian Technology Accelerator (CTA) San Francisco – Life Sciences is an intensive program run by CLS, in conjunction with the Consulate General of Canada in San Francisco. It offers high potential emerging Canadian life science companies strategic guidance and tailored resources to help expand their business in a global hub for the life sciences sector. We focus on providing entrepreneurs in biopharmaceuticals, digital health, medical devices, imaging, precision medicine/genetics, research tools, and diagnostics with customized advisory and in-market programming to advance their commercialization strategies, both in their home market and the United States. This annual program combines remote meetings with on site sessions in San Francisco, culminating with presentations at the FAST Showcase.


For non-U.S.-based clusters seeking to grow their regional economies, FAST International helps life science researchers and early-stage companies gain commercial footholds in U.S. markets and connects them to the resources required to develop subsidiaries or commercial spin-offs in the United States.

FAST International: Scandinavia

The Nordic Mentor Network for Entrepreneurship (NOME) has joined forces with CLS to give Nordic Life Science startups access to potential partners and capital in one of the world’s most innovative regions through our FAST program.  The annual six-day program includes sessions on U.S. Markets and Funding Opportunities and the U.S. Regulatory and Reimbursement environments, as well as focused one-on-one meetings with advisory teams customized to meet the needs of the company with which they will work. The NOME companies also present alongside our FAST cohort at the FAST Closing Showcase along with other international early stage life science companies.


For non-U.S.-based clusters seeking to grow their regional economies, FAST International helps life science researchers and early-stage companies gain commercial footholds in U.S. markets and connects them to the resources required to develop subsidiaries or commercial spin-offs in the United States.

FAST International: United Kingdom (Scotland)

CLS has been working with the Queen’s Medical Research Institute (QMRI) since the fall of 2017.  Based at the BioQuarter in Edinburgh, QMRI utilizes technologies sourced from multiple universities across the United Kingdom with expertise drawn from the University of Edinburgh’s Medical School to develop medtech products aimed at a variety of unmet medical needs.  Located alongside the Royal Infirmary of Edinburgh, QMRI combines deep R&D capabilities with direct clinical access. In particular, CLS collaborates with the University of Edinburgh’s Health Technology Accelerator Facility (HTAF) to offer commercialization advisory services on a variety of proof-of-concept medtech development programs on an ongoing basis.

FAST International: Australia (Queensland)

Trade & Investment Queensland (TIQ) and Life Sciences Queensland (LSQ) partnered with CLS to provide Queensland life sciences companies that have a demonstrated interest in US markets the opportunity to participate in a 12-week accelerator advisory program. Combining in person and virtual multi-day advisory sessions, CLS prepared these companies for entry into the US by concentrating on the scale and complexity of the US ecosystem and, importantly, on regulatory considerations and financial markets. The CLS team also prepared the program participants for presentations and partnering meetings taking place during the J.P. Morgan Annual Healthcare Conference in San Francisco.

FAST International: Japan (Kansai)

CLS and Bayer Yakuhin, in collaboration with Sysmex, the Kyoto University Medical Science and Business Liaison Organization (KUMBL), the City of Kobe, and the Foundation for Biomedical Research and Innovation at Kobe (FBRI) together run the annual Kansai Life Science Accelerator Program for nurturing and supporting life science startups in the Kansai region of Japan.  Together, we are helping to build a vibrant startup culture to supplement the strong academic programs and mature life science industry in Kansai. Combining a community of healthcare-related businesses, advanced specialty hospitals, and research institutions, we are establishing an ecosystem that creates new technologies and business models in the life sciences.

Experienced US life science business professionals (angel investors, serial entrepreneurs, and industry experts) serve as dedicated advisors for the participating startups, leveraging their real-world experience to help these young companies overcome an array of commercialization challenges.  Advisory sessions initially concentrate on the development of a strong business model and later focus on communicating that model to potential investors or strategic partners through presentations.  Each program concludes with an opportunity for the participating companies to present to a combined Japanese/US audience.

FAST International: Japan (Tokyo)

The Tokyo Metropolitan Government seeks to build a biotech cluster utilizing the resources of the region, supplemented by additional expertise. Sponsored by the government, Blockbuster Tokyo supports that goal through a variety of means including seminar programs and accelerator programs for pharmaceutical and medical startupsOne such program, operated by Beyond Next Ventures (BNV) is an acceleration initiative for pharmaceutical and medical startups aims to encourage the establishment and growth of pharmaceutical and medical startups by providing various forms of support to address many of the challenges these startups face.

Beyond Next Ventures joined forces with CLS to support and grow the potential of highly motivated Japanese entrepreneurs who are developing revolutionary technologies. BNV and CLS are working in synchrony with a common goal: to commercialize these technologies for public benefit. In 2020 and early 2021, CLS partnered with BNV to provide FAST advisory commercialization services to ten (10) emerging life science companies from Japan. The program took place between October and January, during which the companies are iterating their business plans and vetting their commercialization strategies with teams of industry experts who have been selected on the basis needs of each company’s needs. The Japanese companies gained introductions through the CLS network and the local life sciences community and explored partnerships and collaborations with pharma and academic entities in one of the world’s most innovative regions- California!